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doi: 10.3389/fphar.2022.1037528 Received 06 September 2022 Accepted 13 December 2022 Published 04 January 2023 Volume 13 - 2022 Edited by Sho Kanzaki, National Institute of Sensory Organs, Japan Reviewed by Chi-Rei Wu, China Medical University, Taiwan Rüdiger Christoph Pryss, Julius Maximilian University of Würzburg, Germany Updates Copyright © 2023 Liu, Hu, Wang, Han, Wang, Wang, Zhou, Ma and Dong

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870 Exposure of chondrocyte to excessive mechanical load leads to increased catabolism